In the event of an overdose, the primary concern is the risk of bleeding. Nurses should:
- Stop LMWH administration immediately. - Monitor for signs of bleeding, both externally and internally. - Administer protamine sulfate: While less effective against LMWH than UFH, protamine sulfate can partially neutralize the anticoagulant effect. - Supportive care: Provide supportive care, including volume replacement and blood transfusions if necessary.