Understanding the lipophilicity of a drug has several clinical implications:
Elderly Patients: Elderly patients often have higher body fat percentages, which can affect the distribution and duration of lipophilic drugs. Obesity: Similar to elderly patients, obese individuals have increased fatty tissues, impacting drug efficacy and safety. Drug Interactions: Lipophilic drugs may interact with other medications metabolized by the liver, requiring close monitoring and dosage adjustments.
