Lipophilicity plays a vital role in how drugs are administered and managed in patient care. Here are some reasons why it's important:
Drug Absorption: Lipophilic drugs can easily penetrate cell membranes, resulting in higher absorption rates. Drug Distribution: These drugs are often distributed widely throughout the body, especially in fatty tissues, which can affect their efficacy and duration. Metabolism: Lipophilic drugs are generally metabolized by the liver. Understanding this can help in predicting drug interactions. Excretion: These drugs are usually excreted through bile rather than urine, impacting how long the drug stays in the body.
