Assessment of GI issues begins with a thorough patient history and physical examination. Key questions include the onset of symptoms, frequency, duration, and characteristics of pain or discomfort. Nurses should ask about dietary habits, medication use, and any associated symptoms such as nausea, vomiting, or diarrhea. Physical examination may involve palpation of the abdomen to detect tenderness, distension, or masses. Vital signs and laboratory tests, including complete blood count (CBC) and liver function tests, are also critical in the assessment process.