Low fibrinogen levels, also known as hypofibrinogenemia, can result from several conditions:
Liver disease: Since fibrinogen is produced in the liver, any liver dysfunction can lead to decreased production. Disseminated Intravascular Coagulation (DIC): This serious condition causes widespread clotting and bleeding, depleting fibrinogen levels. Genetic disorders: Conditions like afibrinogenemia, where fibrinogen is absent, or dysfibrinogenemia, where fibrinogen is dysfunctional, can lead to low levels. Malnutrition: Lack of proper nutrition can impair protein synthesis, including fibrinogen.