major facilitator superfamily (mfs)

What Are the Clinical Implications of MFS in Drug Therapy?

MFS proteins can influence the pharmacokinetics of drugs, affecting their absorption, distribution, metabolism, and excretion. For instance, overexpression of certain MFS proteins can lead to decreased drug efficacy by pumping out therapeutic agents from target cells. Conversely, inhibition of these proteins can enhance drug retention and efficacy. Nurses must be aware of these dynamics to manage drug dosing effectively and mitigate potential side effects.

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