RAAS inhibitors, such as ACE inhibitors and ARBs, work by blocking different parts of the RAAS. ACE inhibitors prevent the conversion of angiotensin I to angiotensin II, thus reducing vasoconstriction and aldosterone release. ARBs block the binding of angiotensin II to its receptors, preventing its effects on blood vessels and aldosterone secretion. These drugs are essential in the treatment of hypertension and heart failure.