Ensuring compliance with the prescribed IV antibiotic regimen is crucial. Nurses play a role in educating patients and their families about the importance of completing the course of antibiotics, even if symptoms improve. Safety is maintained by adhering to the âfive rightsâ of medication administration: Right patient, Right drug, Right dose, Right route, and Right time. Additionally, nurses must keep accurate records and documentation, reflecting each administration and any patient responses or side effects observed.