The IRB is critical in nursing research for several reasons: 1. Ethical Oversight: It ensures that the research adheres to ethical principles, such as respect for persons, beneficence, and justice. 2. Risk Minimization: The IRB assesses potential risks to participants and ensures that these risks are minimized. 3. Informed Consent: It verifies that informed consent is obtained from all participants, ensuring they are fully aware of the study's nature and any potential risks. 4. Regulatory Compliance: The IRB ensures that research complies with federal regulations, state laws, and institutional policies.