Pressure should be applied in several scenarios, including: - Bleeding Control: When a patient is experiencing uncontrolled bleeding, applying direct pressure can help stop the flow of blood. - Wound Care: To promote clot formation and minimize bleeding in minor wounds. - Venipuncture and IV Therapy: Applying pressure post-procedure to prevent hematoma formation. - Edema Management: Compression therapies, such as bandages or stockings, are used to manage swelling and improve venous return.