Bicarbonate (HCO3-) is an anion that plays a crucial role in maintaining the body's acid-base balance. It is a form of carbon dioxide (CO2) that is dissolved in the blood and acts as a buffer to neutralize excess acids. Bicarbonate is regulated by the kidneys and is a part of the bicarbonate-carbonic acid buffer system, which is vital for maintaining the pH of blood and other bodily fluids.