Several factors can influence the need for medication adjustment, including:
Age: Older adults may require dose adjustments due to changes in metabolism. Weight: Dosage often needs to be tailored to a patient's body weight. Renal and hepatic function: Impaired kidney or liver function can affect drug metabolism and excretion. Drug interactions: Concurrent use of multiple medications may necessitate adjustments to prevent adverse drug reactions. Patient adherence: Non-compliance may require regimen modifications for better adherence.