To become a Nurse Practitioner, one must first obtain a Bachelor of Science in Nursing (BSN) and become a registered nurse (RN). After gaining some clinical experience, the next step is to pursue a graduate degree in nursing, such as a Master of Science in Nursing (MSN) or a Doctor of Nursing Practice (DNP). Specialized training and certification in a specific area, such as family practice or pediatrics, are also common and enhance an NPâs skills and marketability.