What are the Challenges in Treating Gram Negative Bacterial Infections?
Treating Gram negative bacterial infections poses several challenges: - Antibiotic Resistance: Many Gram negative bacteria produce enzymes like beta-lactamases that degrade antibiotics, rendering them ineffective. - Limited Treatment Options: The outer membrane of Gram negative bacteria acts as a barrier to many antibiotics, limiting the options available. - Biofilm Formation: Some Gram negative bacteria can form biofilms, which protect them from antibiotics and the immune system, making infections persistent and difficult to eradicate.
