What are Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)?
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) are a class of antiretroviral drugs used primarily in the treatment of HIV/AIDS. These drugs work by inhibiting the reverse transcriptase enzyme, which is crucial for the replication of HIV. Unlike nucleoside reverse transcriptase inhibitors (NRTIs), NNRTIs bind directly to the enzyme and cause a conformational change that disrupts its function.