In the event of a naltrexone overdose, immediate medical attention is required. Symptoms of overdose may include severe nausea, vomiting, and dizziness. While naltrexone itself is not life-threatening, an overdose can exacerbate liver issues. Nurses should be prepared to manage symptoms and provide supportive care. It is crucial to educate patients on the importance of adhering to prescribed doses to prevent accidental overdose.