Drug clearance can be measured using various methods, depending on the drug and the clinical setting. Techniques include:
Blood Plasma Concentration: Measuring the concentration of the drug in the blood over time to calculate clearance rates. Urine Collection: Collecting urine over a specific period to measure the amount of drug excreted. Creatinine Clearance: Often used as a surrogate marker for renal clearance, particularly for drugs excreted unchanged by the kidneys.