Clostridium infections can occur through various routes:
1. Antibiotic Use: Broad-spectrum antibiotics can disrupt normal gut flora, allowing Clostridium difficile to proliferate. 2. Wound Contamination: Tetanus and gas gangrene can occur if Clostridium spores enter a wound. 3. Foodborne Illness: Botulism often results from ingesting improperly canned or preserved foods containing Clostridium botulinum spores.
