The measurement of Anti Xa levels is typically indicated in specific clinical situations, including:
1. Patients with renal impairment: Renal dysfunction can alter the pharmacokinetics of anticoagulants. 2. Pregnancy: Physiological changes during pregnancy can affect drug metabolism. 3. Obesity: Body weight can influence drug distribution and efficacy. 4. Pediatric patients: Children may have different pharmacodynamics compared to adults. 5. Suspected overdose or underdose: Clinical signs of bleeding or thrombosis warrant testing.
