Rabeprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach. It is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and ulcers. Rabeprazole helps in healing acid damage to the stomach and esophagus, prevents ulcers, and may help prevent cancer of the esophagus.