Several factors influence the determination of the correct dosage:
Patient Age: Pediatric and geriatric patients often require adjusted dosages due to differences in body composition and metabolism. Body Weight: Dosages are frequently calculated based on the patient's body weight, especially in pediatrics and critical care. Renal and Hepatic Function: Impaired kidney or liver function can affect drug metabolism and excretion, necessitating dosage adjustments. Comorbidities: Chronic conditions such as diabetes or heart disease can influence how a drug is metabolized and its effectiveness. Drug Interactions: The presence of other medications can alter the effectiveness or increase the toxicity of the prescribed drug.
