Nurses should be aware of various tax deductions and credits available to them. Work-related expenses, such as uniforms and continuing education, may be deductible. Additionally, nurses should consider contributing to tax-advantaged accounts like Health Savings Accounts (HSAs) if they have a high-deductible health plan. HSAs offer triple tax benefits: contributions are tax-deductible, earnings grow tax-free, and withdrawals for qualified medical expenses are tax-free.