What are the Side Effects of Modulating Glutamate Receptors?
While targeting glutamate receptors offers therapeutic potential, it also comes with significant risks. Overactivation of these receptors can lead to excitotoxicity, resulting in neuronal damage and cell death. Conversely, underactivation can impair cognitive functions. Therefore, any pharmacological intervention must be carefully balanced to avoid adverse effects such as seizures, cognitive impairment, and mood disturbances.
