Immediate intervention is critical in managing anaphylaxis. The primary treatment is the administration of epinephrine. Nurses should: - Administer intramuscular epinephrine promptly, usually in the mid-outer thigh. - Position the patient appropriately; lying flat with legs elevated can help maintain blood pressure. - Ensure airway patency and provide oxygen if needed. - Monitor vital signs and prepare for advanced medical interventions if the patient does not respond to initial treatment. - Reassure and comfort the patient while maintaining close observation for symptom progression.