What are the Disadvantages of Oral Administration?
Delayed Onset of Action: Oral medications may take longer to exhibit effects compared to other routes, such as intravenous administration. First-pass Metabolism: Some drugs are extensively metabolized in the liver before reaching systemic circulation, reducing their efficacy. Gastrointestinal Issues: Oral administration can cause irritation or discomfort in the digestive tract, leading to issues like nausea or vomiting.
