While HFNC is generally safe, there are some potential complications and precautions that nurses should be aware of: - Nasal Dryness or Bleeding: Despite humidification, some patients may experience nasal dryness or bleeding. - Gastric Distension: High flow rates can sometimes lead to gastric distension and discomfort. - Skin Irritation: Prolonged usage can cause skin irritation around the nostrils. - Monitoring: Continuous monitoring of oxygen saturation and respiratory parameters is crucial to avoid hyperoxia or hypoxia.