What Are the Clinical Implications of MATE in Nursing?
1. Drug Resistance: Overexpression of MATE transporters can lead to multidrug resistance, particularly in cancer cells. Nurses should be aware of this when administering chemotherapy. 2. Drug Efficacy: MATE transporters can affect the efficacy of drugs such as metformin, a common medication for type 2 diabetes. Understanding this can help in better management of blood sugar levels. 3. Toxicity: Impaired MATE function can lead to the accumulation of toxic compounds, necessitating careful monitoring of patients with liver or kidney diseases.
