Hypercalcemia can be caused by various factors. Some common causes include: - Primary Hyperparathyroidism: Overactivity of one or more of the parathyroid glands. - Malignancies: Certain cancers, such as lung cancer and multiple myeloma, can increase calcium levels. - Medications: Prolonged use of certain medications like thiazide diuretics. - Immobilization: Prolonged bed rest can lead to bone resorption. - Vitamin D Overdose: Excessive intake of vitamin D supplements.