AKI can have multiple causes, which are often categorized into prerenal, intrinsic, and postrenal. Prerenal causes are typically due to conditions that reduce blood flow to the kidneys, such as severe dehydration, heart failure, or sepsis. Intrinsic causes include direct damage to the kidneys from toxins, infections, or autoimmune diseases. Postrenal causes are usually due to obstructions in the urinary tract, such as kidney stones or tumors.