Multidrug Resistant Organisms (MDROs) are bacteria that have developed resistance to multiple antibiotics, making infections harder to treat. This resistance can lead to increased morbidity, mortality, and healthcare costs. Common MDROs include Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococci (VRE), and certain strains of Klebsiella pneumoniae and Escherichia coli.