Several factors can compromise structural integrity, including:
1. Pressure Ulcers: Caused by prolonged pressure on the skin, often in bedridden patients. 2. Infections: Bacterial, viral, or fungal infections that can break down skin and underlying tissues. 3. Trauma: Physical injuries such as fractures, sprains, or cuts. 4. Chronic Conditions: Diseases like diabetes that can impair wound healing and tissue health.