What are Common Drug Interactions Involving Cytochrome P450?
Drugs that are metabolized by the same CYP450 enzyme can potentially interact with each other. For example, if two drugs are metabolized by CYP3A4, one drug can inhibit or induce the enzyme, affecting the metabolism of the other drug. This can lead to either increased toxicity or decreased efficacy of one or both drugs. Common examples include interactions between certain antibiotics and statins.