Calculate Basal Metabolic Rate (BMR) using equations like the Harris-Benedict formula or the Mifflin-St Jeor formula. Estimate the Thermic Effect of Food (TEF), which typically accounts for about 10% of daily caloric intake. Assess the Physical Activity Level (PAL) by categorizing the patient's activity level (sedentary, lightly active, moderately active, very active, or extra active). Combine these components to get the TDEE: TDEE = BMR + (BMR x TEF) + (BMR x PAL)