Nurses should follow a structured approach when handling mandatory referrals: 1. Assessment: Conduct a thorough assessment of the patient's condition to determine the need for a referral. 2. Documentation: Clearly document the reasons for the referral in the patient's medical record. 3. Communication: Communicate effectively with the patient and their family about the need for the referral and what it entails. 4. Coordination: Coordinate with other healthcare providers to ensure a smooth transition of care. 5. Follow-Up: Follow up with the patient and the referred specialist to ensure that the necessary care is being provided.