REE can be measured using indirect calorimetry, which is considered the gold standard. This method calculates energy expenditure by measuring oxygen consumption and carbon dioxide production. However, indirect calorimetry is not always feasible in all healthcare settings due to its cost and complexity. In such cases, predictive equations like the Harris-Benedict equation or the Mifflin-St Jeor equation are used to estimate REE based on factors like age, gender, weight, and height. Despite being less accurate, these equations provide a practical alternative for estimating energy requirements.
