How Does the Blood-Brain Barrier Affect Medication Administration?
The BBB is highly selective, which means that many medications cannot pass through it. This presents a challenge in treating neurological disorders such as Alzheimer's disease, Parkinson's disease, and brain tumors. Nurses must understand the pharmacokinetics of drugs that can cross the BBB and those that cannot. For instance, lipid-soluble drugs are more likely to penetrate the BBB, whereas water-soluble drugs are less likely to do so.
