Various tools and instruments are used to measure QoL, including questionnaires, interviews, and scales. Commonly used instruments include the Short Form Health Survey (SF-36), the European Organization for Research and Treatment of Cancer QoL Questionnaire (EORTC QLQ-C30), and the World Health Organization Quality of Life (WHOQOL) instruments. These tools assess multiple domains such as physical functioning, emotional well-being, social functioning, and pain levels.