Fick's Law, formulated by Adolf Fick in the 19th century, describes the rate of diffusion of a substance across a membrane. In the context of nursing, understanding this principle is crucial for numerous clinical applications, particularly in respiratory care, pharmacology, and wound management. The law is mathematically represented as: J = -D (dC/dx), where J is the diffusion flux, D is the diffusion coefficient, dC is the change in concentration, and dx is the change in distance.